Azithromycin 250 (Azipro 250)

Azipro 250mg Tablets contain the active ingredient azithromycin, a macrolide antibiotic renowned for its broad-spectrum activity against a variety of bacterial infections. Azithromycin works by inhibiting bacterial protein synthesis, effectively stopping the growth and reproduction of bacteria. This medication is particularly effective in treating infections in various body systems.

Indications:

Azipro 250mg Tablets are indicated for the treatment of:

• Respiratory Tract Infections: Such as pneumonia, bronchitis, and sinusitis.
• Skin and Soft Tissue Infections: Including cellulitis and impetigo.
• Ear Infections: Effective for otitis media and external ear infections.
• Sexually Transmitted Infections: Including chlamydia and gonorrhea.
• Pharyngitis/Tonsillitis: Caused by streptococcal bacteria.

Dosage and Administration:

• The dosage of Azipro 250mg can vary based on the infection being treated:
  • For Respiratory Tract Infections: A common regimen involves taking a loading dose of 500 mg on the first day, followed by 250 mg once daily for the next 4 days.
  • For Chlamydia Infections: A single dose of 1 gram (1000 mg) may be prescribed.
• Azipro 250mg Tablets can be taken with or without food, but taking them at the same time each day is recommended to maintain steady drug levels in the bloodstream.

Contraindications:

• Hypersensitivity to azithromycin or any macrolide antibiotics.
• Patients with a history of jaundice or liver impairment related to previous azithromycin use.

Precautions:

• Liver Function: Use with caution in patients with hepatic impairment; liver function should be monitored.
• QT Interval Prolongation: Azithromycin may prolong the QT interval; caution is advised for patients with a history of cardiac arrhythmias or those taking other medications that may affect heart rhythm.
• Pregnancy and Breastfeeding: Should be used during pregnancy or lactation only if the benefits outweigh potential risks and after consulting a healthcare provider.

Side Effects:

Common side effects may include:

• Nausea and vomiting
• Diarrhea or loose stools
• Abdominal pain
• Headache
• Fatigue or dizziness

Serious side effects (seek immediate medical attention if these occur):

• Severe allergic reactions (e.g., difficulty breathing, swelling of the face or throat)
• Liver dysfunction (signs include jaundice, dark urine, or pale stools)
• Severe skin reactions (e.g., rash, blistering)
• Cardiac issues (e.g., palpitations, lightheadedness)

Drug Interactions:

• Azithromycin may interact with other medications that affect liver enzymes (particularly those that induce or inhibit the CYP3A4 pathway), such as certain antihistamines, antifungals, and anticoagulants. Always inform your healthcare provider about all medications, supplements, and herbal products you are taking.

Storage:

• Store at room temperature (15-30°C or 59-86°F), in a cool, dry place away from direct sunlight and moisture.
• Keep out of reach of children.

Packaging:

Azipro 250mg Tablets are usually available in blister packs or bottles, with the quantity based on the prescribed treatment regimen.