Augmentin 625mg Duo Tablets are a combination antibiotic formulation that contains Amoxicillin, a broad-spectrum penicillin antibiotic, and Potassium Clavulanate, a beta-lactamase inhibitor. This combination enhances the effectiveness of Amoxicillin against beta-lactamase-producing bacteria, making it a potent choice for treating various bacterial infections.
Indications:
Augmentin 625mg Duo is indicated for the treatment of various infections caused by susceptible organisms, including:
- Respiratory Tract Infections: Such as pneumonia, bronchitis, and sinusitis.
- Ear, Nose, and Throat Infections: Including otitis media and pharyngitis.
- Skin and Soft Tissue Infections: Such as cellulitis and wound infections.
- Urinary Tract Infections: Including cystitis and pyelonephritis.
- Dental Infections: Such as periodontitis and dental abscesses.
Dosage and Administration:
- Recommended Dosage: The usual adult dosage is one tablet (625mg) taken every 8 to 12 hours, depending on the severity of the infection and physician’s recommendation.
- Duration of Treatment: Treatment duration typically ranges from 5 to 14 days, based on the type and severity of the infection. It is essential to complete the full course of antibiotics, even if symptoms improve, to prevent the development of antibiotic resistance.
- Administration: Augmentin should be taken with food to enhance absorption and reduce gastrointestinal side effects.
Contraindications:
- Hypersensitivity to Amoxicillin, Clavulanate, or any components of the formulation.
- A history of severe allergic reactions (e.g., anaphylaxis) to penicillins or cephalosporins.
- Patients with a history of liver dysfunction associated with Augmentin use.
Precautions:
- Hepatic Impairment: Use with caution in patients with liver disease, as dosage adjustment may be necessary.
- Renal Impairment: In patients with renal impairment, the dosage may need to be adjusted based on renal function.
- Antibiotic-Associated Diarrhea: Patients should be informed about the risk of Clostridium difficile-associated diarrhea, which may occur during or after antibiotic treatment.
Side Effects:
Common side effects may include:
- Nausea and vomiting
- Diarrhea
- Abdominal pain
- Skin rash
- Headache
Serious side effects (seek immediate medical attention if these occur):
- Allergic reactions (e.g., swelling of the face, lips, or throat, difficulty breathing)
- Liver dysfunction (e.g., jaundice, dark urine)
- Severe gastrointestinal symptoms (e.g., persistent diarrhea, bloody stools)
Drug Interactions:
- Augmentin may interact with other medications, including anticoagulants (e.g., warfarin) and certain diuretics (e.g., furosemide). Inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential interactions.
Storage:
- Store at room temperature (15-30°C or 59-86°F) in a dry place, away from direct sunlight and moisture.
- Keep out of reach of children.
Packaging:
Augmentin 625mg Duo Tablets are typically available in blister packs or bottles, with quantities based on the prescribed treatment regimen.
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