Clarithromycin 500mg ( claribid) Tablets

Clarithromycin 500mg (Claribid) Tablets are a macrolide antibiotic used to treat a variety of bacterial infections. Clarithromycin works by inhibiting bacterial protein synthesis, effectively stopping the growth of bacteria. It is effective against a wide range of gram-positive and some gram-negative bacteria.

Indications:

Clarithromycin 500mg is indicated for the treatment of various infections caused by susceptible organisms, including:

• Respiratory Tract Infections: Such as pneumonia, bronchitis, and sinusitis.
• Skin and Soft Tissue Infections: Including cellulitis, impetigo, and other skin infections.
• Ear, Nose, and Throat Infections: Such as otitis media and pharyngitis.
• Helicobacter pylori Eradication: Used in combination therapy for the treatment of H. pylori infection in peptic ulcer disease.

Dosage and Administration:

• Recommended Dosage: The usual adult dosage is 500mg taken every 12 hours. For certain infections, higher doses may be recommended based on the physician’s discretion.
• Duration of Treatment: The treatment duration typically ranges from 7 to 14 days, depending on the specific infection and the patient’s response.
• Administration: Clarithromycin tablets can be taken with or without food. It is recommended to take them at the same time each day for consistent therapeutic levels.

Contraindications:

• Hypersensitivity to clarithromycin or any components of the formulation.
• History of cholestatic jaundice or liver dysfunction related to prior use of clarithromycin.

Precautions:

• Hepatic Impairment: Use with caution in patients with liver disease; dose adjustment may be required.
• Renal Impairment: Dosage modification may be necessary for patients with renal dysfunction.
• QT Interval Prolongation: Caution is advised in patients with a history of arrhythmias or those on medications that prolong the QT interval.

Side Effects:

Common side effects may include:

• Nausea and vomiting
• Diarrhea or abdominal pain
• Taste disturbances (dysgeusia)
• Headache
• Dizziness

Serious side effects (seek immediate medical attention if these occur):

• Allergic reactions (e.g., rash, itching, swelling of the face, lips, or throat, difficulty breathing)
• Severe gastrointestinal symptoms (e.g., persistent diarrhea, bloody stools)
• Liver dysfunction (e.g., jaundice, dark urine)

Drug Interactions:

• Clarithromycin may interact with other medications, including anticoagulants (e.g., warfarin), statins, and certain antiretrovirals. Always inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential interactions.

Storage:

• Store at room temperature (15-30°C or 59-86°F) in a dry place, away from direct light and moisture.
• Keep out of reach of children.

Packaging:

Clarithromycin 500mg Tablets are typically available in blister packs or bottles, with quantities based on the prescribed treatment regimen.