Doxycycline 100mg Capsules are a broad-spectrum antibiotic belonging to the tetracycline class. Doxycycline is effective against a wide range of gram-positive and gram-negative bacteria, as well as certain protozoa. It works by inhibiting bacterial protein synthesis, thereby preventing the growth and reproduction of bacteria.
Indications:
Doxycycline 100mg is indicated for the treatment of various infections, including:
- Respiratory Tract Infections: Such as pneumonia, bronchitis, and sinusitis.
- Skin and Soft Tissue Infections: Including acne and cellulitis.
- Urinary Tract Infections: Such as cystitis and pyelonephritis.
- Sexually Transmitted Infections: Including chlamydia and gonorrhea.
- Rickettsial Infections: Such as Rocky Mountain spotted fever and typhus.
- Malaria Prophylaxis: For individuals traveling to malaria-endemic areas.
Dosage and Administration:
- Recommended Dosage: The usual adult dosage is 100mg taken every 12 hours on the first day, followed by 100mg once daily or as directed by a healthcare provider.
- Duration of Treatment: Treatment duration varies depending on the type of infection, usually ranging from 7 to 14 days.
- Administration: Doxycycline capsules should be taken with a full glass of water. It is recommended to take them with food to minimize gastrointestinal discomfort, but avoid taking them just before lying down to prevent esophageal irritation.
Contraindications:
- Hypersensitivity to doxycycline or any components of the formulation.
- Use in children under the age of 8 years or during pregnancy (due to the risk of tooth discoloration and effects on bone growth).
Precautions:
- Renal and Hepatic Impairment: Use with caution in patients with renal or hepatic dysfunction.
- Sun Sensitivity: Doxycycline may increase sensitivity to sunlight; patients should be advised to avoid excessive sun exposure and use sunscreen.
- Esophageal Irritation: Caution is advised in patients with a history of esophageal disease.
Side Effects:
Common side effects may include:
- Nausea and vomiting
- Diarrhea or abdominal discomfort
- Esophageal irritation
- Dizziness
- Photosensitivity (increased sun sensitivity)
Serious side effects (seek immediate medical attention if these occur):
- Allergic reactions (e.g., rash, itching, swelling of the face, lips, or throat, difficulty breathing)
- Severe gastrointestinal symptoms (e.g., persistent diarrhea, bloody stools)
- Liver dysfunction (e.g., jaundice, dark urine)
Drug Interactions:
- Doxycycline may interact with other medications, including anticoagulants (e.g., warfarin), antacids, and certain anticonvulsants. Always inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential interactions.
Storage:
- Store at room temperature (15-30°C or 59-86°F) in a dry place, away from direct light and moisture.
- Keep out of reach of children.
Packaging:
Doxycycline 100mg Capsules are typically available in blister packs or bottles, with quantities based on the prescribed treatment regimen.
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