Flucloxacillin 500mg (Staphonex) Capsules

Flucloxacillin 500mg (Staphonex) Capsules are a beta-lactam antibiotic that belongs to the penicillin class. It is particularly effective against staphylococcal infections, including those caused by penicillinase-producing strains. Flucloxacillin works by inhibiting the synthesis of bacterial cell walls, leading to bacterial cell death.

Indications:

Flucloxacillin 500mg is indicated for the treatment of various bacterial infections, including:

• Skin and Soft Tissue Infections: Such as cellulitis, impetigo, and infected wounds.
• Bone and Joint Infections: Including osteomyelitis and septic arthritis.
• Respiratory Tract Infections: Such as pneumonia and lung abscesses caused by susceptible organisms.
• Endocarditis: Treatment of bacterial endocarditis caused by staphylococci.
• Urinary Tract Infections: Such as cystitis and pyelonephritis caused by susceptible organisms.

Dosage and Administration:

• Recommended Dosage: The usual adult dosage is 500mg taken every 6 hours, but it may vary based on the severity and type of infection.
• Duration of Treatment: The treatment duration typically ranges from 7 to 14 days, depending on the infection and clinical response.
• Administration: Flucloxacillin capsules should be taken on an empty stomach, ideally 30 minutes before meals, to enhance absorption.

Contraindications:

• Hypersensitivity to flucloxacillin, other penicillins, or any components of the formulation.
• History of severe allergic reactions (e.g., anaphylaxis) to beta-lactam antibiotics.

Precautions:

• Renal Impairment: Use with caution in patients with renal dysfunction; dose adjustment may be necessary.
• Liver Function: Caution is advised in patients with hepatic impairment.
• History of Allergy: Patients with a history of allergy to other antibiotics should be carefully evaluated before use.

Side Effects:

Common side effects may include:

• Nausea and vomiting
• Diarrhea
• Abdominal pain
• Allergic reactions (e.g., rash, itching)

Serious side effects (seek immediate medical attention if these occur):

• Severe allergic reactions (e.g., difficulty breathing, swelling of the face, lips, or throat)
• Liver dysfunction (e.g., jaundice, dark urine)
• Colitis (inflammation of the colon, which may present as severe diarrhea)

Drug Interactions:

• Flucloxacillin may interact with other medications, including anticoagulants (e.g., warfarin) and other antibiotics. Always inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential interactions.

Storage:

• Store at room temperature (15-30°C or 59-86°F) in a dry place, away from direct light and moisture.
• Keep out of reach of children.

Packaging:

Flucloxacillin 500mg Capsules are typically available in blister packs or bottles, with quantities based on the prescribed treatment regimen.