Levofloxacin 250mg (Levoflox 250) Tablets

Levofloxacin 250mg (Levoflox 250) Tablets are a broad-spectrum fluoroquinolone antibiotic used to treat a variety of bacterial infections. Levofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, and repair, ultimately leading to the death of susceptible bacteria.

Indications:

Levofloxacin 250mg is indicated for the treatment of the following infections:

• Respiratory Tract Infections: Including pneumonia, chronic bronchitis, and sinusitis.
• Urinary Tract Infections: Such as cystitis and pyelonephritis.
• Skin and Soft Tissue Infections: Including infected wounds and cellulitis.
• Bone and Joint Infections: Such as osteomyelitis.
• Intra-abdominal Infections: In combination with other antibiotics.

Dosage and Administration:

• Recommended Dosage: The typical adult dosage is 250mg to 750mg, taken once daily, depending on the type and severity of the infection. The dosage may vary based on the healthcare provider’s discretion.
• Duration of Treatment: Treatment duration typically ranges from 5 to 14 days, depending on the specific infection and clinical response.
• Administration: Levofloxacin tablets can be taken with or without food. It is recommended to take them at the same time each day for consistent therapeutic levels.

Contraindications:

• Hypersensitivity to levofloxacin or other fluoroquinolone antibiotics.
• A history of tendon disorders related to fluoroquinolone use.

Precautions:

• Renal Impairment: Dose adjustment may be necessary for patients with renal dysfunction.
• QT Interval Prolongation: Caution is advised in patients with a history of arrhythmias or those on medications that prolong the QT interval.
• Diabetes: Monitor blood glucose levels closely in diabetic patients, as fluoroquinolones can cause fluctuations.

Side Effects:

Common side effects may include:

• Nausea and vomiting
• Diarrhea
• Headache
• Dizziness
• Insomnia

Serious side effects (seek immediate medical attention if these occur):

• Allergic reactions (e.g., rash, itching, swelling of the face, lips, or throat, difficulty breathing)
• Tendon rupture or pain (especially in the Achilles tendon)
• Severe gastrointestinal symptoms (e.g., persistent diarrhea, bloody stools)

Drug Interactions:

• Levofloxacin may interact with other medications, including antacids, sucralfate, and certain antiarrhythmics. Always inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential interactions.

Storage:

• Store at room temperature (15-30°C or 59-86°F) in a dry place, away from direct light and moisture.
• Keep out of reach of children.

Packaging:

Levofloxacin 250mg Tablets are typically available in blister packs or bottles, with quantities based on the prescribed treatment regimen.