Naproxen 250mg (Naprosyn) Tablets

Naproxen 250mg (Naprosyn) Tablets are nonsteroidal anti-inflammatory drugs (NSAIDs) used to relieve pain, inflammation, and fever. Naproxen works by inhibiting cyclooxygenase (COX) enzymes, which play a role in the production of prostaglandins, chemicals that cause inflammation, pain, and swelling in the body. This medication is commonly used to manage pain associated with various conditions, including arthritis, musculoskeletal injuries, and menstrual cramps.

Indications:

Naproxen 250mg is indicated for the treatment of the following conditions:

• Osteoarthritis and Rheumatoid Arthritis: For the relief of pain and inflammation associated with these chronic conditions.
• Acute Gout: To alleviate the symptoms of pain and inflammation during an acute gout attack.
• Musculoskeletal Injuries: Including sprains, strains, and sports injuries.
• Dysmenorrhea (Menstrual Pain): To relieve moderate to severe menstrual cramps.
• Ankylosing Spondylitis: For the treatment of pain and stiffness in the spine.
• Mild to Moderate Pain Relief: Such as headache, toothache, and postoperative pain.

Dosage and Administration:

• Recommended Dosage: The typical adult dose is 250mg to 500mg, taken twice daily, depending on the condition being treated.
• Maximum Dosage: Do not exceed 1000mg per day unless specifically directed by a healthcare provider.
• Administration: Naproxen tablets should be taken with food or a full glass of water to reduce the risk of stomach irritation. Avoid lying down immediately after taking the medication.

Contraindications:

• Hypersensitivity to naproxen or other NSAIDs.
• History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.
• Active gastrointestinal bleeding or peptic ulcer disease.
• Severe renal or hepatic impairment.

Precautions:

• Gastrointestinal Risk: NSAIDs, including naproxen, increase the risk of gastrointestinal bleeding, ulceration, and perforation, especially in older adults.
• Cardiovascular Risk: NSAIDs may increase the risk of serious cardiovascular events, such as heart attack and stroke, particularly in patients with pre-existing cardiovascular conditions.
• Renal Impairment: Use with caution in patients with impaired renal function, as NSAIDs can further reduce kidney function.
• Pregnancy and Breastfeeding: Naproxen should be avoided in the third trimester of pregnancy and used with caution during breastfeeding.

Side Effects:

Common side effects may include:

• Nausea and vomiting
• Stomach pain or indigestion
• Dizziness or headache
• Heartburn
• Constipation or diarrhea

Serious side effects (seek immediate medical attention if these occur):

• Signs of gastrointestinal bleeding (e.g., black, tarry stools, vomiting blood)
• Severe allergic reactions (e.g., difficulty breathing, swelling of the face, lips, or throat)
• Chest pain, weakness, slurred speech (signs of a heart attack or stroke)
• Signs of liver or kidney problems (e.g., yellowing of the skin, dark urine, reduced urination)

Drug Interactions:

• Naproxen may interact with anticoagulants (e.g., warfarin), other NSAIDs, corticosteroids, and certain antihypertensives (e.g., ACE inhibitors).
• Inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential interactions.

Storage:

• Store at room temperature (15-30°C or 59-86°F) in a dry place, away from direct light and moisture.
• Keep out of reach of children.

Packaging:

Naproxen 250mg Tablets are typically available in blister packs or bottles, with quantities based on the prescribed treatment regimen.