Imiquimod 5% (Imiquad) Cream

Imiquimod 5% (Imiquad) Cream is a topical immunomodulatory medication used to treat specific skin conditions by stimulating the body’s immune system. Imiquimod works by activating immune cells and promoting the release of cytokines, which help to fight abnormal skin growths caused by viruses or other skin disorders. It is commonly prescribed for the treatment of actinic keratosis, superficial basal cell carcinoma, and external genital and perianal warts (caused by the human papillomavirus, HPV).

Imiquimod does not directly kill viruses or cancer cells but encourages the immune system to respond to the abnormal tissue, promoting healing and the clearance of lesions.

Indications:

Imiquimod 5% (Imiquad) Cream is indicated for:

• Actinic keratosis (AK): Treatment of AK on the face or scalp in patients with normal immune systems.
• Superficial basal cell carcinoma (sBCC): Treatment of small, superficial forms of basal cell carcinoma in patients who cannot undergo surgical treatment.
• External genital and perianal warts: Treatment of warts caused by HPV in the genital or anal area.

Dosage and Administration:

• For Actinic Keratosis (AK): Apply Imiquimod 5% cream to the affected area twice a week for 16 weeks, or as directed by a healthcare provider.
• For Superficial Basal Cell Carcinoma (sBCC): Apply 5 times a week for 6 weeks to the affected area.
• For Genital and Perianal Warts: Apply 3 times a week until warts disappear, up to a maximum of 16 weeks.
• Imiquimod cream should be applied before bedtime and left on the skin for approximately 6-10 hours. The area should then be washed with mild soap and water. The cream should be applied only to the affected area and should not be covered with occlusive dressings.

Contraindications:

• Hypersensitivity to imiquimod or any of its ingredients.
• Not recommended for use in pregnant women unless clearly needed.

Precautions:

• Avoid contact with eyes, lips, and nostrils.
• Treatment area may become red, swollen, or irritated, which is a sign that the immune system is responding. If severe skin reactions occur, consult a healthcare provider.
• Avoid sun exposure on the treated area as it may increase sensitivity to sunlight.
• Use in pediatric patients is not recommended unless advised by a healthcare provider.

Side Effects:

Common side effects may include:

• Local skin reactions such as redness, swelling, itching, burning, or irritation.
• Skin peeling or flaking.
• Flu-like symptoms (such as fatigue, fever, muscle aches) may occur in some patients.

Serious side effects (seek medical attention if these occur):

• Severe skin reactions such as blistering or ulceration.
• Signs of an allergic reaction (such as rash, itching, swelling, or difficulty breathing).

Drug Interactions:

• There are no known significant drug interactions with Imiquimod. However, inform your healthcare provider about any other medications or topical treatments you are using.

Storage:

• Store at room temperature, away from moisture and heat.
• Keep out of reach of children.
• Discard any unused cream after completing the treatment cycle.

Packaging:

• Imiquimod 5% (Imiquad) Cream is typically available in single-use sachets (250 mg per sachet) for easy application.