Low Dose Naltrexone (LDN) 3mg Tablets are a lower-dose formulation of naltrexone, a drug originally developed to treat opioid and alcohol dependence. At this low dose, LDN is increasingly used for its potential therapeutic effects on the immune system, inflammation, and mood regulation. LDN has been used off-label to help manage autoimmune diseases, chronic pain conditions, and various inflammatory disorders. It is thought to work by temporarily blocking opioid receptors, which can stimulate endorphin production, reduce inflammation, and enhance immune system function.
Indications:
Low Dose Naltrexone (LDN) 3mg Tablets are indicated for:
- Off-label use in managing autoimmune diseases such as multiple sclerosis (MS), rheumatoid arthritis, Hashimoto’s thyroiditis, lupus, and Crohn’s disease.
- Management of chronic pain conditions like fibromyalgia and neuropathic pain.
- Supportive therapy in certain cancer treatments and in patients with chronic inflammatory conditions.
- Enhancing mood and well-being in patients with chronic illness.
Dosage and Administration:
- Recommended Dosage: The starting dose for LDN is typically 3mg, taken once daily, usually in the evening. Dosage may be adjusted based on individual response and tolerance, under the guidance of a healthcare provider.
- The tablet should be taken orally with or without food, and it is important to adhere to the prescribed schedule without exceeding the recommended dosage.
Contraindications:
- Hypersensitivity to naltrexone or any of its ingredients.
- Use in patients currently dependent on opioid medications or those who have used opioids within the past 7-10 days.
Precautions:
- LDN should not be used by individuals who are currently taking opioid painkillers, as it may cause withdrawal symptoms.
- Regular monitoring by a healthcare provider is recommended to adjust the dosage and assess effectiveness.
Side Effects:
Common side effects may include:
- Sleep disturbances (such as vivid dreams or insomnia)
- Nausea or digestive upset
- Headaches
- Fatigue or low energy
Serious side effects (seek medical attention if these occur):
- Severe allergic reactions (including rash, itching, swelling, or difficulty breathing)
- Signs of liver dysfunction (yellowing of the skin or eyes, dark urine)
Drug Interactions:
- LDN may interact with opioid medications and should not be taken concurrently with opioids. Patients should inform their healthcare provider of any other medications or supplements they are taking to prevent possible interactions.
Storage:
- Store at room temperature, away from moisture and direct sunlight.
- Keep out of reach of children.
Packaging:
- Low Dose Naltrexone (LDN) 3mg Tablets are available in bottles or blister packs, typically containing 30 tablets.
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