Metformin 1000mg(glycomet 1000gm)

Glycomet 1000mg Tablets contain Metformin Hydrochloride, an oral antihyperglycemic agent that is primarily used to manage blood glucose levels in patients with type 2 diabetes mellitus. Metformin works by decreasing hepatic glucose production, improving insulin sensitivity, and enhancing glucose uptake by peripheral tissues. It helps to control blood sugar levels effectively when used in conjunction with a proper diet and exercise.

Indications:

• Management of type 2 diabetes mellitus in adults, especially in overweight patients.
• May be used alone or in combination with other antidiabetic medications when diet and exercise alone do not provide adequate glycemic control.

Dosage and Administration:

• The typical starting dose is 500mg to 1000mg, taken orally, usually in two to three divided doses with meals to minimize gastrointestinal side effects.
• The maximum recommended dose is 2000mg to 3000mg per day, depending on individual patient needs and physician recommendations.
• Dosage adjustments should be based on blood glucose levels and tolerability.

Contraindications:

• Hypersensitivity to Metformin or any of the excipients.
• Severe renal impairment (eGFR <30 mL/min) or acute or chronic metabolic acidosis, including diabetic ketoacidosis.
• Patients undergoing procedures requiring the use of contrast media should discontinue Metformin before and for 48 hours after the procedure.

Precautions:

• Monitor renal function regularly, as Metformin can cause lactic acidosis in patients with renal impairment.
• Use with caution in patients with a history of pancreatitis, liver disease, or alcohol abuse.
• Pregnant or breastfeeding women should consult their healthcare provider before using this medication.
• Maintain adequate hydration and dietary management to support effective glycemic control.

Side Effects:
Common side effects may include:

• Nausea
• Diarrhea
• Abdominal discomfort
• Loss of appetite

Serious but less common side effects include:

• Lactic acidosis, a rare but serious condition characterized by metabolic acidosis with increased lactate levels.
• Vitamin B12 deficiency with prolonged use, which may lead to anemia.

Drug Interactions:

• Certain medications, such as diuretics, corticosteroids, and other antihyperglycemic agents, may interact with Metformin, affecting blood glucose levels.
• Inform your healthcare provider of all medications, supplements, or herbal products being taken to avoid potential interactions.

Storage:

• Store at room temperature, below 30°C (86°F), away from moisture and heat.
• Keep out of reach of children.

Packaging:
Available in blister packs, with each tablet containing 1000mg of Metformin Hydrochloride.