Naltrexone 50mg (Nodict) Tablets are an oral medication used to help individuals maintain sobriety by blocking the effects of opioids and reducing the urge to drink alcohol. Naltrexone belongs to the class of opioid antagonists, which work by binding to opioid receptors in the brain without activating them. This action helps prevent the euphoric and sedative effects of opioids and reduces cravings for alcohol. Naltrexone is commonly used as part of a comprehensive treatment program that includes counseling and support for individuals recovering from opioid dependence or alcohol use disorder.
Indications:
Naltrexone 50mg (Nodict) Tablets are indicated for:
- The treatment of alcohol dependence by reducing alcohol cravings and the desire to drink.
- The treatment of opioid dependence by preventing the effects of opioids, such as euphoria, in individuals who have completed detoxification.
Dosage and Administration:
- Recommended Dosage: The typical dosage for alcohol and opioid dependence is one 50mg tablet taken once daily.
- Naltrexone should be taken orally with or without food. It is important to follow the prescribed treatment plan and dosing schedule closely.
- Note: Before starting Naltrexone for opioid dependence, patients must be opioid-free for at least 7-10 days to avoid precipitated withdrawal symptoms.
Contraindications:
- Hypersensitivity to naltrexone or any of its components.
- Current use of opioid analgesics or active opioid dependence.
- Acute hepatitis or liver failure.
Precautions:
- Naltrexone may cause liver toxicity at high doses, so liver function should be monitored regularly during treatment.
- Patients should carry identification stating that they are taking Naltrexone, as the use of opioids while on Naltrexone can result in life-threatening opioid overdose.
- Abrupt discontinuation of Naltrexone should be avoided without medical supervision.
Side Effects:
Common side effects may include:
- Nausea
- Headaches
- Fatigue
- Dizziness
- Insomnia or sleep disturbances
Serious side effects (seek medical attention if these occur):
- Liver toxicity (indicated by yellowing of the skin or eyes, dark urine)
- Allergic reactions (such as rash, itching, swelling, difficulty breathing)
Drug Interactions:
- Naltrexone blocks the effects of opioid medications, so it should not be used in combination with opioids. Inform your healthcare provider of any other medications or supplements being taken to avoid potential interactions.
Storage:
- Store at room temperature, away from moisture and direct sunlight.
- Keep out of reach of children.
Packaging:
- Naltrexone 50mg (Nodict) Tablets are available in blister packs or bottles, typically containing 10 or more tablets.
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