Pirfenex 400mg Tablet

Pirfenex 400mg Tablets contain the active ingredient pirfenidone, an innovative antifibrotic medication used primarily for the treatment of idiopathic pulmonary fibrosis (IPF). Pirfenidone works by inhibiting the processes that lead to fibrosis in the lungs, thus slowing disease progression and improving respiratory function in patients diagnosed with IPF.

Indications:

Pirfenex 400mg Tablets are indicated for the treatment of:

• Idiopathic Pulmonary Fibrosis (IPF): A progressive lung disease characterized by the scarring of lung tissue, leading to difficulty in breathing and reduced quality of life.

Dosage and Administration:

• The standard recommended dosage of Pirfenex is typically 600 mg taken three times a day (totaling 1800 mg daily), which can include the administration of Pirfenex 400mg Tablets as part of the regimen.
• Treatment usually starts at a lower dose to assess tolerance, followed by gradual increases to the target dose based on the patient’s response and any side effects.
• It is advised to take the tablets with food to enhance absorption and minimize gastrointestinal side effects.

Contraindications:

• Hypersensitivity to pirfenidone or any of its components.
• Severe liver impairment (Child-Pugh Class C).

Precautions:

• Liver Monitoring: Regular liver function tests are essential, as pirfenidone can cause elevations in liver enzymes.
• Photosensitivity: Patients should be advised to avoid excessive sun exposure and utilize sun protection, as pirfenidone may increase the risk of skin reactions.
• Pregnancy and Lactation: The safety of pirfenidone during pregnancy and breastfeeding has not been established. Patients should consult their healthcare provider before use.

Side Effects:

Common side effects may include:

• Nausea and vomiting
• Diarrhea
• Fatigue
• Anorexia (loss of appetite)
• Rash or skin reactions

Serious side effects (seek medical attention if these occur):

• Liver function abnormalities (elevated liver enzymes)
• Severe skin reactions
• Worsening of respiratory symptoms
• Signs of an allergic reaction (e.g., swelling, difficulty breathing)

Drug Interactions:

• Pirfenidone may interact with medications that affect liver enzymes, particularly those that induce or inhibit the CYP450 system. Patients should provide their healthcare provider with a complete list of all medications, supplements, and herbal products they are using.

Storage:

• Store at room temperature (15-30°C or 59-86°F), away from light and moisture.
• Keep out of reach of children.

Packaging:

Pirfenex 400mg Tablets are typically available in blister packs or bottles, with quantities determined by the prescribed treatment regimen.